Transactions on Materials, Biotechnology and Life Sciences

About the Journal

Transactions on Materials, Biotechnology and Life Sciences (TMBLS) aims to publish peer-reviewed proceedings from conferences in all fields of materials science and technology, chemical and pharmaceutical sciences, biotechnology, life sciences.

Current Issue

Vol. 8 (2025): 4th International Conference on Modern Medicine Technology and Clinical Science (MMTCS 2025)

Dates: August 30-31, 2025

Venue: Tokyo, Japan

Editors: Deirdre Whitman, Huiyan Liu

ISSN: 2960-1932, eISSN: 2960-2319

ISBN: 978-1-961651-46-3

Conference Link: http://www.mmtcs.org

Published: 11-10-2025

Preface

Preface: 4th International Conference on Modern Medicine Technology and Clinical Science (MMTCS 2025)

Deirdre Whitman, Huiyan Liu

I
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Articles

p53 Correlation with Triple-negative Breast Cancer and Potential Treatments

Yucheng Bi

1-8
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Applications of the Tumor Microenvironment in Breast Cancer Treatment

Siyu Huo

9-16
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Immune Checkpoint Inhibitors: Review, Challenge and Future Prospect

Ruitong Pan

17-25
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Risk Factors and Current Therapeutic Approaches for Hepatocellular Carcinoma

Jiahui Wu

26-33
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Research on the Effects of Hormone Changes on Long-Term Prognosis and Intervention Strategies in Adolescent Depression

Xin Sheng

34-38
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Evaluating the Efficacy of Immune Checkpoint Inhibitors Across Different Cancer Types: Focusing on Lung Cancer, Breast Cancer and Melanoma

Nuoyang Jia

39-44
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Immunotherapy Targeting HER2-positive Breast Cancer

Chingman Tan

45-52
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Assessment of the Potential of Cardiac Glycosides as New Stars in Cancer Treatment

Yixuan Li

53-58
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Evaluation of the Application Value of Optogenetics Technology in the Development of Immunotherapy Methods for Tumors

Huishan Chen

59-63
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Immunological Insights and Translational Advances in HSV-2 Infection and Vaccine Development

Yumin Min

64-70
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Optimizing CAR-T Therapy through CRISPR technology

Yuchen Liu

71-76
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Recent Development in NSCLC Immunotherapies: Mechanisms, Advantages and Research Findings

Jun Gu

77-82
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Applications of Artificial Intelligence in Cancer Precision and Personalized Medicine

Shili Sun

83-88
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Biological Characterization of iPSCs and Its Applications

Feiyuan Zheng

89-93
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Lung Cancer Pathogenesis and Therapeutic Advances

Yupei Zhang

94-98
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Application and Future Development of Metal Stable Isotopes in Tumor Therapy

Zihan Xu

99-105
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Cancer Immunotherapy: Review, Advancement and Future Outlook

Zizhao Zhang

106-112
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Application of Resting-State fMRI in Auxiliary Diagnosis of Dissociative Disorders: Advances in Cerebral Biomarker Research and Clinical Implications

Yitian Yuan

113-117
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Virtual Connection and Real Alienation: A Psychological Path Analysis of the Effect of Cell Phone Use Intensity on Loneliness - With Realistic Social Avoidance as a Mediating Variable

Yanfei Zhu

118-124
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Exploring the Effects of Intimate Relationships on Depression and Anxiety in College Students

Zhe Ding

125-132
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Research Progress on the Influence of People from Childhood Trauma to Fear of Compassion

ZhiLong Cheng

133-136
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Analyzation of the Influence of Video Games on Young People’s Social Satisfaction

Shixin Zheng

137-141
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The Impact of Artificial Intelligence Tools on College Students' Academic Self-efficacy

Xinyu Chen

142-148
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Exploring the Mechanisms of Déjà Vu: Neurological and Psychological Perspectives

Ziqin Xu

149-154
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Personalized Neoantigen Vaccines and CAR-T Cell Therapy: A New Frontier in Cancer Immunotherapy

Langyan Zhu

155-162
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Advances and Challenges in CAR-NK Cell Therapy for Tumor Immunotherapy

Bohan Liu

163-169
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Circadian Regulation of the Immune System and Susceptibility to COVID-19

Zitong Zeng

170-176
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Effect of Music on the Brain’s Memory Processes

Xinhui Wen

177-182
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Efficacy and prognosis of different interventional psychiatric treatments for patients with severe depression

Yuze Lai, Jichong Zhou

183-187
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The Impact of Learning Environment on Students' Procrastination Behavior and Learning Efficiency

Miaohan Yu

188-193
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Analysis of the relationship between deferred examination and test anxiety among Chinese college students: an empirical study based on South China Normal University

Changqi Yu

194-201
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Traditional and Recurrent Spheno-Orbital Meningioma (SOM) Comparison and Treatment Methods

Xuanyu Liu

202-207
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The Impact of Sibling Presence on Individual Social Competence

Ziyi Yang

208-213
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The Relationship Between Negative Experiences In Childhood And Mental Health

Tianqi Xie

214-219
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Correlation Between Peer Pressure And Learning Efficiency

Lingyi Qiao

220-225
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A Review of the Neurobiological Mechanisms and Treatment Options of ADHD Across Different Age Groups

Yixuan Li

226-230
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Neural Mechanism and Educational Interventions for Children with ADHD: From Brain Science to Classroom Practice

Runyao Wang

231-237
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Treatment For Anterior Cruciate Ligament (ACL) Injury

Ke Xu

238-241
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Application Of Traditional Chinese Medicine In The Field Of Prevention And Treatment Of Influenza A

Sutong Li

242-248
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The Mechanism Of Action Of EGFR In Cancer Development And Targeted Therapy And Its Optimization Strategy

Lexin Jin

249-253
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Molecular Diagnostic Approaches For Sickle Cell Anemia

Wenbo Huan

254-259
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Risk Factors, Pathophysiology, And Treatments Of Acute Ischemic Stroke

Boyu Xie

260-265
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Advances In The Research And Application Of Cytokines In Human Cancer Treatment

Xuanlin LU

266-274
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Current Status Of Immunotherapy For Cervical Cancer

Yibao Yu

275-281
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Computational Optimization Of Purmorphamine-Derived Small Molecule Modulators Targeting The Secretin Receptor (SCTR) For Antihypertensive Therapy

Yuhao Xi

282-289
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Engineering Strategies And Therapeutic Applications Of In Vivo Anti-Tumor Gene Delivery Platforms

Yuan Liu

290-297
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The Relationship Between Diet And Cardiovascular Diseases And The Application Of Dietary Patterns In Treatment

Ximeng Yang

298-303
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Pathogenesis And Treatment Of Rheumatoid Arthritis Based On Inflammation

Jinwen Zhu

304-309
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Mechanism And Application Status Of CAR-T Cell Immunotherapy

Yunuo Liu

310-314
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Research Status And Development Trend Of Monoclonal Antibodies For Non-Small Cell Lung Cancer

Minghui Gao

315-319
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Effect of Resveratrol on Major Gynecological Tumors

Renqin Wang

320-325
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Bridging Traditional Wisdom and Modern Diagnostics: Optimizing Chronic Kidney Disease Management through Technological Integration of Traditional Chinese Medicine and Western Medicine

Shiqi Lan

326-336
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Advances in Immunotherapy of Biomarkers for Non-small Cell Lung Cancer Based on Radiomics

Yifei Deng

337-343
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Transplantation of Hematopoietic Stem Cells in Tumor Therapy

Jiefu Deng

344-348
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Progress in the study of drug resistance mechanism of Salmonella

Ruoyao Liu

349-356
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Addressing Antimicrobial Resistance: Evidence-Based Strategies And Innovations

Wenrui Jiang

357-364
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Potential And Challenges Of Phage Therapy: An Alternative Strategy In The Post-Antibiotic Era

Xin Wang

365-376
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Advances In The Application Of Click Chemistry In The Research Of Targeted Therapeutic Drugs

Yue Zhang

377-382
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Nature as Medicine: Exploring Health Benefits of Forest Bathing

Yijia Li

383-390
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Covalent Inhibitors Targeting FabH: A Cutting-edge Strategy in the Development of Novel Antibiotics

Ruize Zhang

391-396
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Clinical Progress of Targeted KRAS Drugs Combined with Immune Checkpoint Inhibitors in the Treatment of Pancreatic Cancer

Lu wang

397-402
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Different Rehabilitation Treatment Methods Used at Meniscus Injury

Ruihaoran Wang

403-407
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The mechanism and effects of traditional Chinese medicine in treating diseases through the regulation of intestinal microbiota

Xiaonan ji

408-412
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Evolving Paradigms in Low-Template DNA Analysis: From Fixed Analytical Thresholds to Probabilistic Modeling

Yilei Zhao

423-431
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Deciphering the Neural Circuits of Consciousness: An Integrative Framework from Microcircuits to Global Networks

Jinhong Wu, Man Li

432-440
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The Growing Threat of Antibiotic Resistance: A Public Health Crisis

Yuhan Liu

441-447
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Role of Mitochondrial Autophagy in Cell Aging and Its Molecular Mechanism

Xinyi Yang

448-453
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Semaglutide as a Novel Therapeutic Agent for Obesity and Type 2 Diabetes

Ruilin Chen

454-459
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Statistical Analysis of COVID-19 Vaccine Effectiveness:A Retrospective Study Based on Global Data

Zhoujie Xie

460-465
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Power of Poop: Identification and Analysis of Gut Microbiome Biomarkers in Diarrhea

Chenxi Hu

466-479
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Local Polio Eradication Programs in Key Endemic Regions in Pakistan: A Scoping Review

Zayna Ilahi

480-491
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The evolving landscape of cancer-causing viruses and clinical trials for vaccine development

Ruoshui Du

492-500
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Research on Transdermal Penetration of Rotigotine Transdermal Patchng

Yuxin Ma

501-507
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Genetic evidence supporting the causal link between optic neuritis and rheumatoid arthritis

Luyue Zhang, Shuting Liu, Jincheng Guo, Jiayuan Yao, Heyi Zhang, Yiwen Zhang, Ting Cheng, Shengxiao Zhang

508-514
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A Personalized Aerobic Exercise Intervention for Chinese Adolescents with Congenital Heart Disease: A Methodological Framework for a Three-Year Longitudinal Study

Zinong Zhu

515-523
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In Vivo CAR-T Therapy: The Transformational Leap Toward Affordable and Safer Cancer Immunotherapy

Leyang Liu

524-535
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Development of a PLA-b-PEG Drug Delivery Carrier Design Framework and ROS pH Responsive Methotrexate Carriers for RA

Jiaxuan (Joseph) Fu

536-550
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Principles and Applications of Vaccine Design Based on Immune Regulatory Networks

Gujue Chang

551-555
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