From Group Intervention to Precision Strike: Insights from Ebola Virus for Future Infectious Disease Management
DOI:
https://doi.org/10.62051/w2yw7a07Keywords:
Ebola virus; Traditional medicine; Precision medicine; Rapid diagnosis; Targeted therapy; Multi-omics technology; Infectious disease prevention and control.Abstract
The 2014–2016 West African Ebola outbreak exposed systemic deficiencies in traditional public health approaches to managing highly lethal infectious diseases, while also marking a transformative turning point for breakthroughs in precision medicine technologies. This study systematically examines the Ebola virus, analyzing its transmission scale and historical challenges in containment. By comparing the effectiveness of traditional medical interventions with rapid diagnostics and targeted therapies, this paper highlights the critical role of precision medicine in infectious disease prevention and control. Research findings demonstrate that CRISPR-based on-site detection significantly reduces diagnostic time, monoclonal antibody drugs (e.g., REGN-EB3) lower mortality rates from 49% to 29%, and multi-omics-driven host-pathogen interaction analyses provide novel pathways for high-risk population screening and personalized vaccine design. Further exploration reveals that precision medicine is shifting infectious disease management from "passive response" to "precision intervention." Finally, article proposes that future infectious disease prevention and control can establish a "prediction-warning-precision intervention" trinity framework, with the expectation of providing reference and basis for subsequent related research.
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