Effect of Resveratrol on Major Gynecological Tumors

Abstract

Breast cancer (BC), cervical cancer (CC), endometrial cancer (EC), and ovarian cancer (OC) are the four most common tumors in women, which seriously threaten women's lives. However, the current mainstream treatment approaches are accompanied by great side effects, and related drugs are scarce. In recent years, researchers have discovered that RES has multiple biological functions and can intervene in the occurrence and development of common gynecological tumors through various pathways, such as inducing cell apoptosis, regulating cell autophagy, affecting cell migration and invasion, and reversing treatment tolerance. However, the instability of RES limits its clinical application, and clinical studies are relatively limited. This paper summarizes and analyzes the mechanism of RES against common gynecological tumors and concludes that RES has great research prospects but certain limitations in its application. It can also provide relevant personnel with a certain theoretical basis and research direction reference, as well. At present, the problems of RES stability and lack of clinical research have not been solved. In the future, we can start with drug development and clinical trials.